I'm PhD student in the Faculty of Physics, Astronomy and Applied Computer Science in Jagiellonian University (Krak闚, Poland) and I work in Joint Institute for Nuclear Research (Dubna, Russia) as a mathematician. I'm interested in mathematical models in radiobiology.
Email: joannadeperas@wp.pl
Screenshots for CABAS and file *.exe
Some softwares with codes for calculations
Mathematical Models in Radiobiology
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Short description:
CABAS is a freeware program devoted to fitting of linear-quadratic dose-response curves for dicentric and ring-type chromosomal aberrations as used in biological dosimetry. The procedure of fitting chromosomal data to a linear-quadratic equation should be performed by the method of maximum likelihood. This method is difficult to apply because it is not implemented in the widely used, low cost statistical software packages. A further difficulty is the correct calculation of the 95% confidence interval of dose on the calibration curve. Although a number of papers have been published were the problem of proper curve-fitting is discussed and different solutions are proposed, these are difficult to implement for people who have no support of a statistician.
Therefore, we decided to develop a freely available tool with the help of which the user can:
- fit chromosomal aberration data to a linear-quadratic equation by maximum likelihood and test the goodness of fit
- calculate the dose and the uncertainty based on the scored frequency of aberrations
- check if the aberration distribution is Poissonian and, in case it is not, calculate the dose received by the exposed part of the body
- estimate the number of cells necessary to detect a given dose of radiation
- calculate the dose in the case of fractionated or protracted exposure to radiation
- calculate the odds ratio of zero dose versus a suspected dose
Laboratory of Information Technologies
Institute of Nuclear Chemistry and Technology
Radiology Info
Health Physics Internet Resources
Radiation Information Network
RADAR - the RAdiation Dose Assessment Resource
Uncertaity of Measurement Results
Health Physics Society
Radiation Protection Dosimetry
Global Dosimetry Solutions
Software(University of Michigan)